The uptime RPC returns the total uptime of the server in seconds.
uptime none
*bitcoin-cli help uptime
uptime Returns the total uptime of the server. Result: n (numeric) The number of seconds that the server has been running Examples: > bitcoin-cli uptime > curl --user myusername --data-binary '{"jsonrpc": "1.0", "id": "curltest", "method": "uptime", "params": []}' -H 'content-type: text/plain;' http://127.0.0.1:8332/